Our Technologies

Elucidating causal relationships between the components within complex networks has impact in commercial and research applications.  For example, the ability to understand causal relationships of the components that determine stock prices can predict how the stock market will behave.  In biomedical research, knowing the relationships between the genes within complex ...

Intracellular signaling pathways mediate cellular responses to a variety of extracellular signals and dysregulation of such pathways, especially those involved in cell growth and differentiation, is the main cause of cancer. The RAS family of proteins plays key roles in signal transduction, and mutations in RAS proto-oncogenes are involved in ...

Dr. Luca Lambertini, co-Director of the Mount Sinai Pregnancy BioBank, and Dr. Men-Jean Lee, Director of Perinatal Research in the Department of Obstetrics, Gynecology and Reproductive Science, have developed a disposable, cylindrically-shaped soft tissue sampling tool that ...

Scientists in Drs. Hoffman and Chaurasia’s laboratories have developed a novel approach to substantially expand the numbers of functional Cord blood (CB) hematopoietic stem cells (HSCs) while maintaining true stem cell engraftment capability. Cord blood (CB) cells that express CD34 have extensive hematopoietic capacity and rapidly ...

Obesity is a major public health problem. Dr. Martignetti and colleagues have described an autosomal-recessive morbid-obesity syndrome and identify the disease-causing gene defect. Homozygosity mapping localized the disease locus to a region in 3q29; we designated this region the morbid obesity 1 (MO1) locus. Sequence analysis identified a ...