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Request for Applications in Cancer-Related Projects

Conduits Experimental Therapeutics & Technology (ET&T) Program,

Tisch Cancer Institute (TCI) and

Mount Sinai Innovation Partners (MSIP)

Jointly Announce

– Request for Applications in Cancer-Related Projects –


Mount Sinai’s Conduits ET&T Program, TCI and MSIP are jointly soliciting applications for pilot projects with start date of April 1, 2014. The purpose of these grants is to encourage cancer research-related collaborative translational projects between clinical and basic scientists, to develop high-risk/high-gain ideas, and to obtain proof-of-principle data to help a research team with more competitive applications to extramural funding agencies. Pilot studies that demonstrate a translational rationale, are multi-disciplinary (involve collaborations between junior & senior investigators and different Institutes/Departments), and have the potential to lead to therapeutic discovery and novel diagnostics are encouraged.

Projects will be funded at $50,000 for one year. Applications must be submitted by two Co-Principal Investigators working collaboratively in a specific area of cancer, or cancer-related disease. Up to 3 awards will be made. Recipients of pilot project grants may seek funding for a second year. Such applications will be evaluated competitively with new projects, and scientific progress will be used as an additional review criterion.

The Application Guidelines

The application should have:

1) A face page listing the title of the grant, and the name(s), department(s) and position(s) of the principal investigator(s).

2) A 250 word scientific abstract.

3) NIH style biosketches of the principal investigator(s), and a listing of current grant support. Overlap with other current grants and pending applications should be clearly identified and described.

4) A detailed budget with 12-month timeline and milestones. Funds may be requested in the Personnel, Supplies, and Other categories only. Salaries for PIs, equipment (over $5,000) and travel are not permitted. A budget justification must be included. Please note that funding is paid out based on project progress and milestones achieved, and that failure to achieve milestone requirements results in halting the project and/or funding.

5) The proposal should be 3 pages in length and describe specific aims, significance and background, and approach. An additional page of references is permitted. One or 2 key recent publications may be included. A timeline for completion of the project is required, and must reflect that there will be no carry-forward.

Applications are submitted as a single PDF document to Arnaldo Medina at Arnaldo.Medina@mssm.edu.

If you have any questions, please contact Rachel Posner at Rachel.Posner@mssm.edu.

Review Process and Timeline

Applications will be reviewed using the NIH review format. All applications will receive written reviews from at least two reviewers. These reviews will be discussed by the Review Overview Committee comprised of senior faculty members who will select the applications for funding.

Application Receipt                            February 14, 2014 – 5:00 PM EST

Notification of Awards                        March 21, 2014

Project Period                                    April 1, 2014 – March 31, 2015

Funding for the successful applications will be initiated upon receipt of applicable GCO, IRB, and IACUC approvals. In order to maintain funding, it is expected that all regulatory approvals (GCO, IRB, IACUC) will be in place within 2 months of the project start date (by June 1, 2014).