Posts Tagged ‘Muskoskeletal Disorders’

The genipin-crosslinked fibrin hydrogel (FibGen) is a stiff, biocompatible hydrogel intended to fill tissue defects in load bearing tissue, and this particular formulation has the addition of fibronectin or collagen to enhance cell viability, proliferation and phenotypic characteristics. Dr. James Iatridis ...

A new paradigm for osteoporosis prevention and treatment was described by Dr. Mone Zaidi, Director of the Mount Sinai Bone Program at the Icahn School of Medicine at Mount Sinai.  By blocking follicle-stimulating hormone (FSH) in pre-clinical models of menopause using an antibody against FSH, bone regeneration was enhanced by ...

Bone homeostasis is a complex process and requires a balance between bone formation and resorption.  Cathepsin K is a collagenase which is highly expressed in bone resorbing cells and its deficiency leads to pycnodysostosis, a rare disease characterized by a decrease in bone resorption. Osteoporosis, a disease in which bones ...